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aggregation activities antiplatelet
New Copper Compounds with Antiplatelet Aggregation Activity
Tests for antiplatelet aggregation activities of all of the four compounds were conducted. Results: X-ray diffraction studies show that (L1) and (L2) exist in the enol-imine tautomeric form with a strong intramolecular hydrogen bond. NMR studies show that both ligands are found as enol-imine tautomers in
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Anti-Platelet Aggregation and Anti-Cyclooxygenase ...
Coffee is rich in caffeine (CF), chlorogenic acid (CGA) and phenolics. Differing types of coffee beverages and brewing procedures may result in differences in total phenolic contents (TPC) and biological activities. Inflammation and increases of platelet activation and aggregation can lead to thromb
More
Anti-platelet aggregation activities of different ...
Jun 20, 2015 1. J Ethnopharmacol. 2015 Jun 20;168:116-21. doi: 10.1016/j.jep.2015.03.013. Epub 2015 Mar 31. Anti-platelet aggregation activities of different fractions in leaves ...
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Anti-inflammatory, Antiplatelet Aggregation, and ...
May 09, 2020 The biological activities of all isolates were evaluated using four types of bioassays including cytotoxicity, anti-inflammatory, antiplatelet aggregation, and antiangiogenesis activities. Compounds 4 and 6 showed potent anti-inflammatory activity, compound 2 possessed potent antiplatelet aggregation and antiangiogenesis activities, and ...
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Platelet Aggregation Pathway Network-Based Approach for ...
Apr 04, 2013 Therefore, antiplatelet aggregation agents may be useful for regulating the platelet aggregation and treating the relative disorders. In this work, we developed a computational approach based on network efficiency and network flux to evaluate the antiplatelet aggregation activities of active ingredients separated from TCM.
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(PDF) Antiplatelet aggregation activity of compounds ...
Rubraxanthone showed inhibitory activity against aggregation caused by the three inducers, and was the most effective antiplatelet compound against collagen-induced platelet aggregation with an ...
MoreAnti-platelet aggregation activities of different ...
Jun 20, 2015 1. J Ethnopharmacol. 2015 Jun 20;168:116-21. doi: 10.1016/j.jep.2015.03.013. Epub 2015 Mar 31. Anti-platelet aggregation activities of different fractions in leaves ...
MoreAnti-Platelet Aggregation and Anti-Cyclooxygenase ...
Coffee is rich in caffeine (CF), chlorogenic acid (CGA) and phenolics. Differing types of coffee beverages and brewing procedures may result in differences in total phenolic contents (TPC) and biological activities. Inflammation and increases of platelet activation and aggregation can lead to thromb
More(PDF) Antiplatelet aggregation activity of compounds ...
Rubraxanthone showed inhibitory activity against aggregation caused by the three inducers, and was the most effective antiplatelet compound against collagen-induced platelet aggregation with an ...
More
Synthesis, Antiplatelet Aggregation Activity Evaluation ...
Feb 09, 2016 A series of novel 6‐alkylamino(alkoxyl)‐2‐propylthio‐8‐azapurine nucleosides were synthesized by an improved route, and the human antiplatelet aggregation activities of these new compounds were evaluated.
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Synthesis and in vitro anti-platelet aggregation ...
In vitro anti-platelet aggregation activities of target compounds were assessed on rabbit platelet by turbidimetric test.[27] ADP, AA, and collagen were employed as inducers of platelet aggregation. Picota-mide and aspirin were used as positive controls. Those compounds which had better inhibitory activities were chosen to calculate IC 50
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Antiplatelet aggregation activity of diterpene alkaloids ...
Aug 02, 2002 3.3.. Comparison of in vitro antiplatelet activities of atisine-type alkaloids with those of ginkgolide B and aspirinA comparison of the inhibitory effects of atisine-type alkaloids, ginkgolide B and aspirin on PAF, arachidonic acid and ADP-induced platelet aggregation is shown in Table 1.Of the 14 test compounds, 12 selectively inhibited platelet aggregation induced by PAF.
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Anti-Platelet Aggregation and Anti-Cyclooxygenase ...
Coffee is rich in caffeine (CF), chlorogenic acid (CGA) and phenolics. Differing types of coffee beverages and brewing procedures may result in differences in total phenolic contents (TPC) and biological activities. Inflammation and increases of platelet activation and aggregation can lead to thrombosis. We focused on determining the chemical composition, antioxidant activity and inhibitory ...
More
Synthesis and Antiplatelet Aggregation Activities in Vitro ...
Sep 23, 2014 The preliminary inhibitory in vitro activities of 19 target compounds 2a-2r of series 2 and 19 control compounds 1a-1r of series 1 on antiplatelet aggregation were evaluated and reported in (Table 2), in order to test the effect of various substituents in the meta-position. The results showed that 7 compounds (2c, 2e, 2g, 2i, 2j, 2l and 2q ...
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New Copper Compounds with Antiplatelet Aggregation ...
Tests for antiplatelet aggregation activities of all of the four compounds were conducted. Results: X-ray diffraction studies show that (L1) and (L2) exist in the enol-imine tautomeric form with a ...
More
Antiplatelet properties of natural products
Although with a much less clear picture, natural dietary compounds have also demonstrated to exert antiplatelet activities, further contributing to reduce the thrombotic risk. This article provides a brief overview of the atherothrombotic process to further provide an up-to-date review of the antiplatelet properties exerted by natural products ...
MoreAnti-inflammatory, Antiplatelet Aggregation, and ...
May 09, 2020 The biological activities of all isolates were evaluated using four types of bioassays including cytotoxicity, anti-inflammatory, antiplatelet aggregation, and antiangiogenesis activities. Compounds 4 and 6 showed potent anti-inflammatory activity, compound 2 possessed potent antiplatelet aggregation and antiangiogenesis activities, and ...
MorePlatelet Aggregation Pathway Network-Based Approach for ...
Apr 04, 2013 Therefore, antiplatelet aggregation agents may be useful for regulating the platelet aggregation and treating the relative disorders. In this work, we developed a computational approach based on network efficiency and network flux to evaluate the antiplatelet aggregation activities of active ingredients separated from TCM.
More
Anti-inflammatory, Antiplatelet Aggregation, and ...
analysis. The biological activities of all isolates were evaluated using four types of bioassays including cytotoxicity, anti-inflammatory, antiplatelet aggregation, and antiangiogenesis activities. Compounds 4 and 6 showed potent anti-inflammatory activity, compound 2 possessed potent antiplatelet aggregation and antiangiogenesis
More
Antiplatelet aggregation and antithrombotic benefits of ...
Particularly, compounds 10 and 24 inhibited ADP-induced platelet aggregation and delayed FeCl3-induced thrombus in zebrafish. Furthermore, interactions between compounds 10 and 24 with two ADP receptors P2Y1 and P2Y12, serving as the target for key regulators of antiplatelet aggregative activity, were investigated via molecular modeling.
MoreAnti-inflammatory, Antiplatelet Aggregation, and ...
May 09, 2020 The biological activities of all isolates were evaluated using four types of bioassays including cytotoxicity, anti-inflammatory, antiplatelet aggregation, and antiangiogenesis activities. Compounds 4 and 6 showed potent anti-inflammatory activity, compound 2 possessed potent antiplatelet aggregation and antiangiogenesis activities, and ...
More(PDF) Antiplatelet aggregation activity of compounds ...
Rubraxanthone showed inhibitory activity against aggregation caused by the three inducers, and was the most effective antiplatelet compound against collagen-induced platelet aggregation with an ...
MoreSynthesis and in vitro anti-platelet aggregation ...
In vitro anti-platelet aggregation activities of target compounds were assessed on rabbit platelet by turbidimetric test.[27] ADP, AA, and collagen were employed as inducers of platelet aggregation. Picota-mide and aspirin were used as positive controls. Those compounds which had better inhibitory activities were chosen to calculate IC 50
MoreAntiplatelet aggregation activity of diterpene alkaloids ...
Aug 02, 2002 3.3.. Comparison of in vitro antiplatelet activities of atisine-type alkaloids with those of ginkgolide B and aspirinA comparison of the inhibitory effects of atisine-type alkaloids, ginkgolide B and aspirin on PAF, arachidonic acid and ADP-induced platelet aggregation is shown in Table 1.Of the 14 test compounds, 12 selectively inhibited platelet aggregation induced by PAF.
MoreSynthesis, Antiplatelet Aggregation Activity Evaluation ...
A series of novel 6‐alkylamino(alkoxyl)‐2‐propylthio‐8‐azapurine nucleosides were synthesized by an improved route, and the human antiplatelet aggregation activities
MoreSynthesis and Antiplatelet Aggregation Activities in Vitro ...
Sep 23, 2014 The preliminary inhibitory in vitro activities of 19 target compounds 2a-2r of series 2 and 19 control compounds 1a-1r of series 1 on antiplatelet aggregation were evaluated and reported in (Table 2), in order to test the effect of various substituents in the meta-position. The results showed that 7 compounds (2c, 2e, 2g, 2i, 2j, 2l and 2q ...
MoreAnti-inflammatory, Antiplatelet Aggregation, and ...
analysis. The biological activities of all isolates were evaluated using four types of bioassays including cytotoxicity, anti-inflammatory, antiplatelet aggregation, and antiangiogenesis activities. Compounds 4 and 6 showed potent anti-inflammatory activity, compound 2 possessed potent antiplatelet aggregation and antiangiogenesis
MoreAnti-Platelet Aggregation and Anti-Cyclooxygenase ...
Coffee is rich in caffeine (CF), chlorogenic acid (CGA) and phenolics. Differing types of coffee beverages and brewing procedures may result in differences in total phenolic contents (TPC) and biological activities. Inflammation and increases of platelet activation and aggregation can lead to thrombosis. We focused on determining the chemical composition, antioxidant activity and inhibitory ...
More
(PDF) Antiplatelet aggregation and cytotoxic activity of ...
Jun 10, 2015 The antiplatelet aggregation activity of the compounds was separately evaluated on collagen, adenosine diphosphate [ADP], thrombin and epinephrine induced rat platelet aggregations.
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Antiplatelet, Antithrombotic, and Fibrinolytic Activities ...
Hence, the C. xanthocarpa extract with a combination of antiplatelet aggregation, antithrombotic, and fibrinolytic activities may be effective in preventing thrombus formation through several pathways. Saponins are widely distributed in plants and have many biological activities, such as antiplatelet
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Synthesis and in vitro activities on anti-platelet ...
Jun 10, 2019 Cardiovascular diseases are the most frequent cause of morbidity and mortality worldwide. In order to discover novel compounds with anti-platelet aggregation activities, a series of novel 4-methoxy-1,3-phthalamidesamides (1a–1i) and a series of novel 4-methoxy-1,3-benzenedisulfon-amides (2a–2i) were synthesized and their anti-platelet aggregation activities were evaluated by the ...
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Antiplatelet and Antioxidant Activities of Tomato
Jun 08, 2019 Antiplatelet and Antioxidant Activities of Tomato. Abdul Waheed Khan 1, , Kashif Iqbal 1, Sagheer Ahmed 2, , Saima Gul 3, Arif-ullah Khan 4, Muhammad Usman 1 and Hafsa Bibi 5. 1 Department of Pharmacy, University of Lahore, Islamabad, Pakistan. 2 Shifa College of Pharmaceutical Sciences, Shifa Tameer-E-Millat University, Islamabad, Pakistan. 3 Department of Physical Therapy,
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Chemical constituents from heartwoods of Caesalpinia ...
Oct 01, 2019 Antiplatelet aggregation activities assay. Institute of Cancer Research (ICR) mice (male, 30−40 g) were obtained from Nanjing Qinglongshan Animal Center (Nanjing, Jiangsu, China). The animals were acclimatized for at least 1 d prior to use. Mouse gel-filtered platelets were prepared as described previously (Su et al., 2016). Briefly, the mice ...
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Hemiterpene Glucosides with Anti-Platelet Aggregation ...
Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy-1-butene-4-O-β-d-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1-butene-4-O-β-d-glucopyranoside, respectively.
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